Generates Dose-response curve fits on cell-based toxicity data. Outliers of replicate data-sets can be removed by setting a threshold for standard deviation (here set to 25). Curve fits for compounds showing low response can be removed by setting a threshold for minimum activity (here set to 75% confluence).
This workflow needs R-Server to run in the back-end. Start R and run the following command: library(Rserve); Rserve(args = "--vanilla")
Workflow
DRC_template_toxicity
Used extensions & nodes
Created with KNIME Analytics Platform version 4.5.2
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KNIME HCS Tools
Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany
Version 4.0.0
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