Dose Response (R)
Calculates and visualizes dose response curves. This is achieved by fitting several non-linear regression models to your data.
Measurements are grouped per Compound and Concentration (see Options).
Measurements from a zero concentration are used to calculate the fit but are not displayed in the plot because of its logarithmic scale.
For a conceptual and technical overview have a look at "Bioassay Analysis using R", Ritz and Streibig, 2005, 5:12, Journal of Statistical Software.
This node is using R as back end, make sure that Rserve is running somewhere, and KNIME is accordingly configured (KNIME->Preferences). HCS-Tools Wiki
- Type: Data A table with dose response data
- Type: Data A table which contains ic50s, model parameters, and error estimates
- Type: Image The generated dose response curve plotted as PNG-image
- Type: de.mpicbg.knime.scripting.r.port.RPortType2 An R list with all dose response models for further analysis
Community Nodes > HCS Tools > Screen Mining
Make sure to have this extension installed: