The Online Chemical Modeling Environment (www.ochem.eu) is a web-based platform that aims to automate and simplify the typical steps required for QSAR modeling. The platform consists of two major subsystems: the database of experimental measurements and the modeling framework. A user-contributed database contains a set of tools for easy input, search and modification of thousands of records. Usually, OCHEM is used via a web interface. OCHEM nodes allow to access a number of features directly in your KNIME workflows. The main features available via OCHEM KNIME nodes include running predictions, export and import of data.