Enrichment Plotter (local)
This node draws enrichment curves often used in virtual screening. For this the user can choose a column by which the data is sorted and represents the x-axis. The values on the y-axis are formed by the sum of the hits in a second column that is also selected by the user. A row is considered a hit if the activity value is greater than 0. The steeper the resulting curve, the better the enrichment is. Optionally the y-axis can show the sum of the activity values instead of the number of hits.
The two gray lines in the view show the enrichment if the data points were ordered randomly (lower diagonal) and the optimal enrichment if all hits are ordered before the first non-hit (upper diagonal).
- Type: Data Input data with values to sort by and actual activity values
- Type: Data A one-column table with the area(s) under the enrichment curve(s)
- Type: Data Table with the discovery rates (either hits or clusters) for the different curves at the selected faction sizes. Also contains the enrichment factors which describe how many times better the given order is compared to a random order.