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SimulateBounds

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Jul 11, 2022 9:45 AM
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It is possible to simulate any number of flux constraints by running UpdateBounds and Run FBA in a loop, but for large set of constraints that approach is timeconsuming. This node provides syntactic sugar for simulation of hundreds and thousands of constraint combinations in one run. It takes the model to simulate and table of reaction bounds in which raws corresponds to reactions and columns to constraints. Cells of the table contains flux bounds for reaction within the particular constraint. Columns defining the lower and upper bounds should be selected via **Lower bounds** and **Upper bounds** dialog respectively. The output of the component is the table with objective values for each constraint.

Component details

Input ports
  1. Type: Python
    model
    cobrapy Model object from other FBA components
  2. Type: Table
    Port 2
Output ports
  1. Type: Table
    fluxes
    table of flux values for the solution

Used extensions & nodes

Created with KNIME Analytics Platform version 4.3.4
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    KNIME Base nodesTrusted extension

    KNIME AG, Zurich, Switzerland

    Version 4.3.4

    knime
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    KNIME Python Integration

    KNIME AG, Zurich, Switzerland

    Version 4.3.3

    knime
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    KNIME Quick FormsTrusted extension

    KNIME AG, Zurich, Switzerland

    Version 4.3.3

    knime

This component does not have nodes, extensions, nested components and related workflows

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