Original repository location here: https://hub.knime.com/knime/spaces/Examples/08_Other_Analytics_Types/02_Chemistry_and_Life_Sciences/07_Gene_Expression_Analysis~vUgr-iyGudXur-1B/current-state This workflow requires R to be installed on your local machine, follow this link to see how it can be done: https://docs.knime.com/latest/r_installation_guide/index.html#_introduction For the 'R Snippet" node to work, you need to go into R and install the library 'edgeR' : https://bioconductor.org/packages/release/bioc/html/edgeR.html For the last component in the workflow you will need to input your credentials to 'Google Authenticator' and you need to add a driver for 'Google BigQuery Connector' node. The link below details how this can be done: https://docs.knime.com/latest/db_extension_guide/index.html#register_jdbc Actual link to driver needed: https://cloud.google.com/bigquery/docs/reference/odbc-jdbc-drivers If using API key, you can follow this on how to get connected: https://www.knime.com/blog/tutorial-importing-data-from-google-bigquery